Today’s top oral stem cell supplements are spirulina, quercetin, astragalus root, olive leaf extract, and glucosamine and chondroitin. These, along with those that are about to be named below, are all backed by studies, with benefits that aren’t only solely helpful to those who seek to improve their overall stem cell health.
Of course, when one of these supplements suddenly becomes unavailable, it also helps when you know its food sources. The same can be said when looking for suitable alternatives of these dietary supplements. Stem cell research is likewise developing every day, coming up with more findings and solutions down the line.
Cerule’s StemEnhance ULTRA is an oral stem cell supplement that benefited from the efforts made collectively by the field that only wanted the best out of stem cells and their efficacy. The supplement, which is also backed by considerable studies and features only the most natural ingredients, is truly in a league of its own.
Top 9 Oral Stem Cell Supplements
1. Fucoidan
According to the National Center for Biotechnology Information, Fucus vesiculosis fucoidan, when administered intravenously, can influence stem cells. This is evidenced by its effect on the mobilization of stem cells in the peripheral circulation in mice and baboons. The same study revealed that an increase in the number of stem cells was also noted when fucoidan was delivered orally.
Top sources:
Brown seaweeds
U. pinnatifida species
Mozuku
Kombu
Limumoui
Bladderwrack
Alternatives:
None
2. Blueberry Extract
A journal article from Oxford Academic revealed that a blueberry extract has significantly increased the rate of proliferation of the adult human progenitor cells (AHNPs) of those patients with Parkinson’s. In addition, the treatment that used blueberry extracts revived the decrease in proliferation and cell viability subsequent to the cellular stress caused by dopamine, an indication of a potential neuroprotective effect.
Top sources:
Blueberries
Blueberry powder
Blueberry extract
Alternatives:
Acai berries
Raspberries
Blackberries
Strawberries
Pomegranate seeds
3. Glucosamine and Chondroitin
An observation obtained from ScienceDirect indicated that glucosamine, when used in treatment, can enhance human mesenchymal stem cells in chondrogenesis. Additionally, it can maintain chondrocytes’ cartilage matrix gene expression, possibly responsible for the supplement’s potential chondroprotective properties on cartilage.
Meanwhile, chondroitin is thought to enhance the ability of a mesenchymal stem cell to transform into cartilage.
Top sources:
- Chicken feet
- Beef trachea
- Bone broth
- Shellfish shells
- Chondroitin doesn’t have any known food sources
Alternatives:
- Fiber
- Flaxseed oil
- Copper
- Alpha-Linolenic Acid (ALA)
4. Spirulina
As per recent studies, it’s been revealed that spirulina may prevent decreases in brain stem cell proliferation that are induced by inflammation and accumulate because of aging. Accordingly, it can increase bone marrow stem cells by at least 10 percent at a high dose. Another study revealed that the blue-green algae type may also encourage stem cell genesis.
Top sources:
The blue-green algae can only be taken as a supplement for now.
Alternatives:
Chia seeds
Goji berries
Acai berries
Golden flax seeds
5. Quercetin
A journal from the BioMed Central shared that quercetin, a flavonoid, features a capacity to promote proliferation in bone marrow mesenchymal stem cells. The same source also revealed that it can enable osteogenic differentiation.
There was also a study that showed that when combined with human umbilical cord mesenchymal stem cells, quercetin regulated tumor necrosis.
Top sources:
Citrus fruits
Sage
Onion
Parsley
Grapes
Dark cherries
Olive oil
Alternatives:
Spirulina
Omega-3 fatty acids
Flaxseed oil
Magnesium
Calcium
Selenium
6. Astragalus Root
Astragalus root is also one of the top herbs that can affect the vitality of your stem cells. Another journal from the National Center for Biotechnology Information showed that the herb’s roots can improve bone marrow mesenchymal stem cells (BMSCs) that are aging. The same study deemed that the roots can affect these stem cells’ osteogenesis.
Research also shows that astragalus root can stimulate the number of stem cells in lymph tissue, encouraging this development to active immune cells.
Top sources:
Astragalus
Alternatives:
Licorice
Dong Quai
Green tea
Ginger
Peppermint
7. Resveratrol
There’s a potent reason most manufacturers of stem cell supplements include resveratrol as one of their ingredients—this plant compound features many effects on stem cell characteristics. At the top of the list is its ability to protect pluripotent stem cells from apoptosis, which is the process of programmed cell death.
In addition, resveratrol can encourage osteogenesis, while inhibiting the human mesenchymal stem cells’ adipogenesis.
Top sources:
Blueberries
Cranberries
Bilberries
Grape juice
Grapes
Wine
Peanuts
Cocoa
Alternatives:
Pterostilbene
Grape Seed extract
Fisetin
8. NMN
NMN (nicotinamide mononucleotide), which plays many vital roles in your body, has also been long associated with the progress in stem cell research. As per most recent studies, the nucleotide can reduce cellular senescence, a dormant state that encourages aging.
Moreover, the effects of NMN on cellular senescence, along with mitochondria, are ruled by sirtuin 3’s increased activity.
Top sources:
Cucumbers
Edamame
Cabbage
Broccoli
Avocados
Mushrooms
Beef
Alternatives:
Nicotinamide Riboside (NR)
Collagen
Coenzyme Q10
Essential Fatty Acids
Resveratrol
9. Olive Leaf Extract
Another promoter of stem cell reproduction is olive leaf extract. This promotion was again established recently by a Japanese company which developed an olive leaf extract capable of enabling stem cell reproduction. Ultimately, the firm also revealed that this can be incorporated in health supplements.
The said stem cell reproduction is made possible through increasing the production of the hypoxia-inducible factor 1, which is a protein type that promotes proliferation and differentiation of stem cells in a low oxygen condition.
Top sources:
Olive plant
Olive leaf powder
Alternatives:
None
Can stem cells be taken orally?
Stem cells cannot be taken orally. In fact, manufacturers that market stem cell supplements containing actual stem cells shouldn’t be believed. Nevertheless, stem cell therapies, which include stem cell supplements, can now be taken orally. There are now stem cell supplements in the market that are both safe and effective.
Do stem cell supplements really work?
Stem cell supplements work. While there's no scientific evidence or published clinical studies that show health supplements containing stem cells capable of treating or preventing a medical condition, stem cell supplements may promote many stem cell characteristics. There are also studies and research associated with stem cell supplements that now show these additives do what they do.
Are oral stem cell supplements effective?
Oral stem cell supplements may be effective. According to sellers of stem cell capsules, their products are 40% to 50% efficacious, as per those who purchased supplements from them. Also, these supplements resulted in marked improvements in their several conditions.
In terms of stem cell proliferation and differentiation, however, evidence that associates stem cell supplements with them is little.
Are oral stem cell supplements FDA approved?
Oral stem cell supplements aren’t approved by the FDA. According to the agency, the only stem cell treatment that's getting its stamp of approval are products that treat specific cancers and blood disorders, along with conditions associated with the immune system.
Here are some of the approved products by the FDA:
ABECMA
BREYANZI
GINTUIT
HPC, Cord Blood
MACI
ZOLGENSMA
What are stem cell supplements majorly used for?
Stem cell supplements are majorly used for the promotion of your overall stem cell health. Studies also revealed that these supplements may help in the proliferation of human stem cells.
Consumers who might benefit from regenerative medicine or a stem cell therapy, which include oral stem cell supplements, are those who experience the following conditions:
Cancer
Osteoarthritis
Alzheimer’s disease
Heart disease
Parkinson’s disease
Type 1 diabetes
Spinal cord injuries
Stroke
Burns
What supplements support stem cell health?
Curcumin/turmeric
Fisetin
Glycine
Vitamin C
L-carnosine
Green tea extract
Leucine
Vitamin D
What are the three supplements that can help boost stem cell production?
Spirulina
Quercetin
Astragalus root
What are the benefits of taking stem cell supplements?
- Improves bodily conditions and functioning
- Aids in the natural production of MSCs
- May provide faster recovery times from illnesses and injuries
- Promotes overall stem cell health
- Brings essential health, beauty, and anti-aging benefits
- Pain relief
What are the side effects of stem cell pills?
There are no known side effects of stem cell pills. However, consumers who underwent stem cell therapies reportedly experienced fatigue, chills, headache, nausea, and low-grade fever.
Before you take stem cell supplements, it is encouraged that you speak with a healthcare practitioner first.
Conclusion
One must always be cautious of the supplements they’re ingesting. While these supplements are generally safe for consumption, it is still so easy to fall prey to those that basically don’t benefit your condition.
These oral stem cell supplements we listed are backed by studies, reputable ones that have already been established time and again. Cerule’s StemEnhance ULTRA stem cell supplement is the byproduct of these efforts, right with its backing of an extensive research, along with ingredients that are all natural and ultimately beneficial to many consumers.
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