The side effects of stem cell supplements include nausea, diarrhea, headache, vomiting, and more. These health risks, along with these supplements’ benefits in our overall stem cell health, are about to be revealed—all of which are backed by research.
Even the top 15 stem cell supplements have accompanying side effects you need to be aware of before trying them. Ultimately, the most important things you need to do before taking the route of stem cell supplements are very crucial steps whenever you finally decide to supplement.
Cerule’s StemEnhance ULTRA stem cell supplement is one dietary supplement that not only promotes the improvement of your overall stem cell health. It also contains natural ingredients, ones that are exclusive and revolutionary. Ultimately, the supplement doesn’t come with side effects that will otherwise direct you to take another route.
Top 15 Stem Cell Supplements and Their Side Effects
1. Cerule’s StemEnhance ULTRA
The dietary supplement that aids in the promotion of human stem cell health from Cerule, the StemEnhance ULTRA stem cell supplement, has also been gaining traction in the market today. This is largely because of its all-natural ingredients, along with its components that are backed by extensive research.
Side effects:
Nausea
Insomnia
Headache
Dizziness
Diarrhea
The StemEnhance ULTRA stem cell supplement features Cerule’s proprietary ingredients, such as Mesenkine, a unique extract from spirulina, and StemEnhance, an Aphanizomenon Flos-Aquae concentrate.
2. Blueberry powder/extracts
A journal article from Oxford Academic revealed that blueberry extracts have beneficial effects on adult human progenitor cells. Additionally, nutrients found in these extracts have also been associated with the promotion of the increase of human bone marrow cells and stem cells.
Side effects:
Constipation
Nausea
Diarrhea
Vomiting
It should be noted, however, that these side effects were only experienced by consumers who had drinks made with freeze-dried blueberries.
3. Fisetin
Recent stem cell research suggests that fisetin can restore muscle stem cell function through the process of elimination of senescent fat stem cells. The flavonoid has also been shown to inhibit osteogenic differentiation of mesenchymal stem cells.
Side effects:
No studies have been made yet regarding fisetin’s side effects in humans. Nevertheless, children and pregnant women are advised not to supplement with it.
4. Vitamin C
Vitamin C has long been linked with stem cell health. One of its benefits pivotal to stem cells is its ability to modulate the function of embryonic stem cells. It’s also been shown to be capable of enhancing the reprogramming of fibroblasts to induced pluripotent stem cells.
Side effects:
Headache
Nausea
Bloating and stomach cramps
Fatigue
Heartburn
When taken in high dosage, Vitamin C may also cause skin flushing, fever, and chills.
5. Glycine
Published studies showed that glycine can encourage the survivability of a subpopulation of stem cells. It’s also been revealed that the amino acid can influence the advancement of the differentiation of neural stem cells.
Side effects:
Drowsiness
Stomach upset
Nausea
Vomiting
The said side effects were only reportedly experienced by a few consumers. Glycine is still generally safe when taken by mouth or used topically.
6. NMN
NMN (Nicotinamide Mononucleotide) has also been shown to promote osteogenesis, much like the other supplements included in the list. The nucleotide has likewise been associated with contemporary stem cell research for its ability to renew bone tissue stem cells.
Side effects:
Nausea
Diarrhea
Indigestion
Flushing
Stomach discomfort
These side effects are only experienced when the NMN is being supplemented at a high dosage.
7. Spirulina
One of the stem cell-boosting supplements in the market today, spirulina has also been shown to prevent inflammation-induced decreases in the proliferation of brain stem cells. The blue-green algae can also promote stem cell genesis.
Side effects:
Nausea
Insomnia
Headache
While considered being safe, spirulina, in its other forms, may still be combined with other harmful compounds that can have detrimental effects such as thinning your blood or worsening autoimmune conditions.
8. Quercetin
Another stem cell-boosting supplement established as of late in stem cell research is quercetin. Accordingly, it can encourage the proliferation of stem cells in human bone marrows. It can also promote osteogenic differentiation through a specific axis.
Side effects:
Stomach upset
Headache
A byproduct of quercetin has also been linked to a loss of protein function. Meanwhile, a very high dosage of quercetin can also cause damage in your kidneys.
9. Astragalus root
According to the National Center for Biotechnology Information, astragalus root can improve mesenchymal stem cells in human bone marrow, especially in terms of osteogenesis and vitality. Astragalus has long been used in Traditional Chinese Medicine and is noted for its rich antioxidant properties, which protect cells against damage.
Side effects:
Itching
Rash
Stomach discomfort
Nasal symptoms
While these health risks have been noted, they are uncommon and only occur when the dosage is well above higher than usual.
10. Leucine
The branched-chain amino acid’s recent studies with stem cell research have also been promising. As per journals, receptors that are abundant in leucine, G-protein-coupled, and repeat-containing are markers of adult human stem cells.
Side effects:
Hypoglycemia
Pellagra
Consumers who are breastfeeding or pregnant are advised not to take supplements containing leucine.
11. Green tea extract
Another enhancer of osteogenesis in human bone marrow’s mesenchymal stem cell line is found in green tea extract or catechin. Its association with this might be a no-brainer for some, as the supplement has long been known for its abundant antioxidant and antibacterial properties.
Side effects:
Tremors
Irritability
Sleeping problems
The component found in green tea, caffeine, is causing these side effects.
12. Glucosamine and chondroitin
Studies show that glucosamine and chondroitin can both influence the promotion of mesenchymal stem cells into cartilage. Glucosamine alone, as per ScienceDirect, can encourage chondrogenic phenotype in both mesenchymal stem cells and chondrocytes. Chondroitin sulfate, on its end, has been established as a modulator of stem cells in human cornea.
Side effects:
Puffy eyelids
Hair loss
Bloating and stomach pain
Nausea
Diarrhea
If you experience irregular heartbeats and swelling in your legs when you’re supplementing glucosamine and chondroitin, reach out to your physician at once.
13. Curcumin/turmeric
Along with green tea, it’s no surprise that curcumin has also been in the spotlight in stem cell research. Curcumin can protect some of your stem cells from toxicity; the encouragement of the proliferation and differentiation of human stem cells is also one of its qualities.
Side effects:
Rash
Headache
Diarrhea
Yellow stool
Consumers who take blood-thinning medications are encouraged not to supplement with curcumin or turmeric.
14. Resveratrol
Resveratrol may easily have the most benefits for human stem cell health. As per studies, it can:
Safeguard pluripotent stem cells from apoptosis.
Promote osteogenesis
Impede adipogenesis in mesenchymal stem cells
Side effects:
Hypersensitivity
Nausea
Diarrhea
Some allergic reactions
Alteration of human blood, cytokine, and liver parameters
People who have conditions that might be exacerbated when exposed to estrogen shouldn’t supplement resveratrol.
15. L-Carnosine
Apart from blueberry and green tea, L-carnosine has also been revealed to promote the increase of stem cells and human bone marrow cells. Meanwhile, the protein building block may help in protecting you against bone marrow degeneration that is worsened as we age.
Side effects:
Nausea
Vomiting
Stomach upset
Headache
Carnosine might also have an effect on blood sugar levels.
What do stem cell supplements do?
Stem cell supplements help promote human stem cell health. Most oral stem cell supplements in the market today are clinically proven to stimulate the production of healthy stem cells in our body. They also aid in the revitalization of damaged cells, while providing many individual health benefits, depending on the ingredients included.
Are stem cell pills good for you?
Stem cell pills are good for you, especially if you intend to take them as supplements. This can be very true for consumers who have just undergone stem cell therapies or treatments, along with those who want to improve their overall health.
Before you supplement, however, it is imperative that you seek advice of a healthcare practitioner first, as stem cell supplements contain ingredients that may interfere or counteract your current medication.
How long does it take for stem cell supplements to work?
It takes months before stem cell supplements work. While some benefits associated with stem cell supplements work or become visible after a few days of taking them, research shows it takes two to three months for these supplements to work.
Manufacturers of these stem cell supplements also advised consumers to take them consistently, so the results are impactful.
Where can stem cell supplements be purchased?
Stem cell supplements can now be purchased online and over the counter. Most manufacturers ship stem cell supplements directly to their buyers, which eliminates the need of a middleman. This also allows buyers to save money.
Do stem cell supplements interact with other drugs?
Stem cell supplements interact with other drugs in ways that may cause problems. For instance, Vitamin K is revealed to reduce the effects of warfarin, a blood-thinning medication that prevents blood from clotting.
St. John’s Wort, a popular mood-boosting supplement, has also been found to be reducing the effectiveness of antidepressants, heart and anti-HIV medications, transplant drugs, and birth control pills.
Vitamin C and E, noted for their antioxidant properties, are also said to lessen the efficacy of some types of cancer chemotherapy treatments.
What can consumers do before taking stem cell supplements?
Consumers must reach out to their healthcare providers first before taking stem cell supplements. These providers include your doctors, pharmacists, and even dietitians who can help you determine which supplements will benefit your health or condition.
Consumers must also do these before taking stem cell supplements:
Steer clear of stem cell supplements that have exaggerated claims.
Avoid supplements that are “approved by FDA.”
Be cautious of marketers who say that consumers have been “cured” because of their supplements.
In addition, it is best that you keep a complete record of any supplements or medications you’re taking. For each supplement or medicine, note the name, along with the dosage, time, and reason you’re consuming them.
Why is there a controversy about using stem cell supplements?
There’s a controversy about using stem cell supplements because of:
Oral placenta supplements containing live stem cells
Stem cells regenerating new and healthy cells
Stem cells preventing and treating medical conditions and diseases
Can older adults take stem cell supplements?
Older adults may take stem cell supplements. However, like any consumer who’s taking them for the very first time, it is suggested that you speak with a healthcare practitioner to determine which supplement best fits your health or condition.
In a 2015 study published in the New England Journal of Medicine, it was revealed that adults 65 and older were more likely to experience hospitalization because of adverse events caused by dietary supplements.
Can children consume stem cell supplements?
Children shouldn’t consume stem cell supplements as most supplements were only tested for humans. Although most of these stem cell supplements do not contain ingredients considered unsafe for children, it is still best that you seek an opinion of your healthcare provider first before taking this route.
Does the FDA approve stem cell supplements?
The FDA does not approve stem cell supplements. The federal agency only oversees dietary supplements. However, the agency can take legal actions against manufacturers who sell dietary supplements that come with deceptive claims or false statements. The same can be said when these companies are promoting these supplements as cures or treatments for diseases.
When stem cell supplements are considered unsafe, the FDA can also prosecute the manufacturers and marketers behind.
What are the side effects of dietary supplements?
Shortness of breath
Rashes
Slurred speech
Blood in the urine
Diarrhea
Severe joint or muscle pain
The said symptoms can vary from less serious to life threatening.
Conclusion
Stem cell supplements are now the rage, and with good reason. These supplements promote our overall stem cell health, with individual benefits that rival some of the best multivitamins in the market.
But with anything good that comes out of a bottle, stem cell supplements must also be taken with guidance and moderation. With Cerule’s StemEnhance ULTRA stem cell supplement, you’re already more than halfway there, right with its all-natural ingredients such as Mesenkine and StemEnhance and research backed extensively.
All you need to do now is take heed of the important things we listed above, starting with you and your healthcare provider discussing how you’ll be taking this journey.
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